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Clarify "Include people with outcomes who are not observed… #103

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Clarify "Include people with outcomes who are not observed… #103

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2 changes: 1 addition & 1 deletion PatientLevelPrediction.Rmd
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Expand Up @@ -460,7 +460,7 @@ The first set of options enable the user to specify the time-at-risk period. Thi

If "**Should subjects without time at risk be removed?**" is set to yes, then a value for "**Minimum time at risk:**" is also required. This allows removing people who are lost to follow-up (i.e. that have left the database during the time-at-risk period). For example, if the time-at-risk period was 1 day from cohort start until 365 days from cohort start, then the full time-at-risk interval is 364 days (365-1). If we only want to include patients who are observed the whole interval, then we set the minimum time at risk to be 364. If we are happy as long as people are in the time-at-risk for the first 100 days, then we select minimum time at risk to be 100. In this case as the time-at-risk start is 1 day from the cohort start, a patient will be included if they remain in the database for at least 101 days from the cohort start date. If we set "Should subjects without time at risk be removed?" to 'No', then this will keep all patients, even those who drop out from the database during the time-at-risk.

The option "**Include people with outcomes who are not observed for the whole at risk period?**" is related to the previous option. If set to "yes", then people who experience the outcome during the time-at-risk are always kept, even if they are not observed for the specified minimum amount of time.
The option "**Include people with outcomes who are not observed for the whole at risk period?**" is related to the previous option. If set to "yes", then people who experience the outcome during the time-at-risk are always kept, even if they are not observed for the specified minimum amount of time. (If a patient had outcome at time-at-risk 60 days and no more observation after that, but the time-at-risk period is set to 365 days, then the patient will be dropped out if you don't set this option yes.)

The option "**Should only the first exposure per subject be included?**" is only useful if our target cohort contains patients multiple times with different cohort start dates. In this situation, picking "yes" will result in only keeping the earliest target cohort date per patient in the analysis. Otherwise a patient can be in the dataset multiple times.

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