diff --git a/packages/mui-base/src/MenuButton/MenuButton.test.tsx b/packages/mui-base/src/MenuButton/MenuButton.test.tsx
index caf7fde2e87504..f3ebf1031ea5f1 100644
--- a/packages/mui-base/src/MenuButton/MenuButton.test.tsx
+++ b/packages/mui-base/src/MenuButton/MenuButton.test.tsx
@@ -1,16 +1,20 @@
 import * as React from 'react';
 import { expect } from 'chai';
 import { spy } from 'sinon';
+import userEvent from '@testing-library/user-event';
 import {
   act,
   createMount,
   createRenderer,
   describeConformanceUnstyled,
-  fireEvent,
 } from '@mui-internal/test-utils';
 import { MenuButton, menuButtonClasses } from '@mui/base/MenuButton';
 import { DropdownContext, DropdownContextValue, DropdownActionTypes } from '@mui/base/useDropdown';
 
+// TODO v6: initialize @testing-library/user-event using userEvent.setup() instead of directly calling methods e.g. userEvent.click() for all related tests in this file
+// currently the setup() method uses the ClipboardEvent constructor which is incompatible with our lowest supported version of iOS Safari (12.2) https://github.com/mui/material-ui/blob/master/.browserslistrc#L44
+// userEvent.setup() requires Safari 14 or up to work
+
 const testContext: DropdownContextValue = {
   dispatch: () => {},
   popupId: 'menu-popup',
@@ -131,32 +135,58 @@ describe('<MenuButton />', () => {
   });
 
   describe('keyboard navigation', () => {
-    ['ArrowUp', 'ArrowDown'].forEach((key) =>
-      it(`opens the menu when pressing ${key}`, () => {
-        const dispatchSpy = spy();
-        const context = {
-          ...testContext,
-          state: { open: false },
-          dispatch: dispatchSpy,
-        };
-
-        const { getByRole } = render(
-          <DropdownContext.Provider value={context}>
-            <MenuButton />
-          </DropdownContext.Provider>,
-        );
-        const button = getByRole('button');
-
-        act(() => {
-          button.focus();
-        });
-
-        fireEvent.keyDown(button, { key });
-
-        expect(dispatchSpy.calledOnce).to.equal(true);
-        expect(dispatchSpy.args[0][0]).to.contain({ type: DropdownActionTypes.open });
-      }),
-    );
+    [<MenuButton />, <MenuButton slots={{ root: 'span' }} />].forEach((buttonComponent) => {
+      const buttonType = buttonComponent.props.slots?.root ? 'non-native' : 'native';
+      ['ArrowUp', 'ArrowDown'].forEach((key) =>
+        it(`opens the menu when pressing "${key}" on a ${buttonType} button`, async () => {
+          const dispatchSpy = spy();
+          const context = {
+            ...testContext,
+            state: { open: false },
+            dispatch: dispatchSpy,
+          };
+
+          const { getByRole } = render(
+            <DropdownContext.Provider value={context}>{buttonComponent}</DropdownContext.Provider>,
+          );
+
+          const button = getByRole('button');
+          act(() => {
+            button.focus();
+          });
+
+          await userEvent.keyboard(`{${key}}`);
+
+          expect(dispatchSpy.calledOnce).to.equal(true);
+          expect(dispatchSpy.args[0][0]).to.contain({ type: DropdownActionTypes.open });
+        }),
+      );
+
+      ['Enter', ' '].forEach((key) =>
+        it(`opens the menu when pressing "${key}" on a ${buttonType} button`, async () => {
+          const dispatchSpy = spy();
+          const context = {
+            ...testContext,
+            state: { open: false },
+            dispatch: dispatchSpy,
+          };
+
+          const { getByRole } = render(
+            <DropdownContext.Provider value={context}>{buttonComponent}</DropdownContext.Provider>,
+          );
+
+          const button = getByRole('button');
+          act(() => {
+            button.focus();
+          });
+
+          await userEvent.keyboard(`{${key}}`);
+
+          expect(dispatchSpy.calledOnce).to.equal(true);
+          expect(dispatchSpy.args[0][0]).to.contain({ type: DropdownActionTypes.toggle });
+        }),
+      );
+    });
   });
 
   describe('accessibility attributes', () => {
diff --git a/packages/mui-base/src/useMenuButton/useMenuButton.ts b/packages/mui-base/src/useMenuButton/useMenuButton.ts
index 5355a6f03f1b86..82a04a688cee67 100644
--- a/packages/mui-base/src/useMenuButton/useMenuButton.ts
+++ b/packages/mui-base/src/useMenuButton/useMenuButton.ts
@@ -80,7 +80,7 @@ export function useMenuButton(parameters: UseMenuButtonParameters = {}): UseMenu
     externalProps: ExternalProps = {} as ExternalProps,
   ) => {
     const externalEventHandlers = extractEventHandlers(externalProps);
-    const getCombinedProps = combineHooksSlotProps(getButtonRootProps, getOwnRootProps);
+    const getCombinedProps = combineHooksSlotProps(getOwnRootProps, getButtonRootProps);
 
     return {
       'aria-haspopup': 'menu' as const,