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modeltest: Candidate models set is empty #68

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liamxg opened this issue Feb 21, 2024 · 2 comments
Open

modeltest: Candidate models set is empty #68

liamxg opened this issue Feb 21, 2024 · 2 comments

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@liamxg
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liamxg commented Feb 21, 2024

Dear @ddarriba,
I set the -m MTZOA,PMB, but it still reported as modeltest: Candidate models set is empty:


modeltest x.y.z
Copyright (C) 2017 Diego Darriba, David Posada, Alexandros Stamatakis
License GPLv3+: GNU GPL version 3 or later http://gnu.org/licenses/gpl.html.
This is free software: you are free to change and redistribute it.
There is NO WARRANTY, to the extent permitted by law.

Written by Diego Darriba.

Physical cores: 4
Logical cores: 8
Memory: 8GB
Extensions: AVX

WARNING: State C is missing in the alignment
WARNING: State F is missing in the alignment
WARNING: State W is missing in the alignment
WARNING: Empirical frequencies will be disabled
WARNING: ... There are 236 more warnings. Check the log file for details
modeltest: Candidate models set is empty

@ddarriba
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Dear @liamxg,
I believe you are trying to evaluate empirical frequencies only (with the -f e argument) in a protein MSA with missing states. Since several states, like C, F, and W, are not present in any sequence, empirical frequencies are disabled to avoid numerical issues. Therefore, there are no models to evaluate. Consider using the model-specific frequencies.

@liamxg
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liamxg commented Feb 23, 2024

Dear @ddarriba,
For this situation, I have two choices: one is use -f f, which is the default setting; another is use model-specific frequencies, right?
BTW, how to set the model-specific frequencies? Thanks.

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